Digitalizing Severity Compliance in Animal Research

PicoTeam InVivo: Connecting welfare data, severity assessment, and compliance reporting

Under EU Directive 2010/63/EU, facilities are required to manage severity classification, welfare observations, cumulative burden assessment, and retrospective reporting with full traceability throughout the study lifecycle.

Many facilities still rely on paper cage cards, spreadsheets, and disconnected systems to manage these processes, creating challenges in documentation, traceability, reporting, and inspection readiness.

PicoTeam InVivo helps research facilities digitalize and standardize these workflows through a connected platform that combines digital cage cards, mobile data capture, and centralized study management.

The platform supports prospective severity planning through standardized welfare monitoring workflows, observation protocols, and scoring frameworks.

Interventions can be recorded directly at the cage side and automatically linked to the animal and study record. This creates a complete digital history that supports retrospective severity reporting, cumulative burden assessment, and refinement activities.

Having access to complete and traceable welfare data helps facilities make more informed severity assessments, identify opportunities for refinement, and simplify regulatory reporting.

Key capabilities supporting severity management and regulatory compliance include:

Severity Classification

      • Structured and standardized severity-related workflows

      • Consistent documentation across studies and teams

    Welfare Monitoring

        • Real-time cage-side observations and clinical findings

        • Immediate access to current welfare information

      Retrospective Reporting

          • Complete procedural and welfare history

          • Centralized reporting and data access

        Cumulative Burden Assessment

            • Full animal lifecycle traceability

            • Visibility into previous procedures, studies, and interventions

          Compliance and Inspection Readiness

              • Automated audit trails

              • Timestamped records and user traceability

              • Inspection-ready documentation

            PicoTeam InVivo helps research facilities transform compliance with EU Directive 2010/63/EU into a connected digital workflow that supports severity management, welfare monitoring, traceability, and regulatory readiness throughout the animal lifecycle.