GLP-compliant research data with cryptographic proof
In regulated research, trust isn’t enough.
When an auditor asks, “Has this data been changed?” — the answer can’t be “we don’t think so.” It needs to be provable.
That’s why PicoTeam InVivo was designed around a simple but powerful principle:
every action is recorded as a permanent, sealed entry in an unbreakable chain.
What conventional audit trails don’t prove
Most systems approach compliance by logging changes alongside the data.
A user updates a record, and a log entry is created somewhere in the system.
But those logs are just more data — stored in the same way, in the same place.
They are not cryptographically sealed.
Which means they can be altered like any other record.
In these systems, you are still relying on trust — not proof.
PicoTeam InVivo: an unbreakable chain
PicoTeam InVivo works differently.
Every action — creating a record, updating a value, adding a note — is stored as a permanent event in a chained structure.
Each event is sealed with a cryptographic fingerprint that includes the fingerprint of the previous event.
That one includes the one before it.
All the way back to the very first recorded action.
Think of it like a notebook written in ink, where every page carries a seal derived from the previous page.
Change one word on page 50, and every seal from page 51 onward breaks.
You cannot alter the past without leaving an unmistakable trace.
In PicoTeam InVivo, this is not an audit trail added on top.
The chain is the system.
Your data and its history are inseparable.
“But what about corrections?”
This is the right question — especially in GLP environments.
GLP does not allow silent changes. Every correction must document:
- what was wrong
- what was changed
- why it was changed
In PicoTeam InVivo, original records are never edited.
Instead, new events are added to the chain:
- corrections
- reversals
- justifications
The original entry remains.
The correction remains.
The reasoning remains.
All permanently recorded. All cryptographically sealed.
This aligns directly with GLP expectations — but instead of relying on procedure, PicoTeam InVivo ensures integrity through mathematics, not policy.
A time machine for your data
Because PicoTeam InVivo stores every event — not just the current state —
you can reconstruct your data exactly as it existed at any point in time.
What did this animal’s record look like last Tuesday at 15:00?
What values were present before a correction?
You don’t need to dig through logs or compare backups.
The full history is embedded in the system.
For researchers, this enables true study traceability.
For auditors, it provides complete transparency.
Verification in one click
In PicoTeam InVivo, data integrity is not assumed — it is verified.
An administrator can validate the entire event chain at any time.
The system checks every cryptographic link from the latest event back to the beginning.
The result is binary:
- intact
- or broken
No interpretation. No grey area.
Even at scale — one million animals, fifty million data points —
full verification completes in under a second.
Proof, not promises
GLP compliance should not depend on trusting that nothing was changed.
It should depend on proving that nothing could be changed without detection.
That is the foundation of PicoTeam InVivo.
Because your data should not rely on trust.
It should prove itself.


